Thank you, John and Mike.
I'm ready to order another box if anything else goes wrong, and to experience the delights of Windows-8. Vista, I will not miss.
After endless fiddling, I've got all the essentials running. This is a 64-bit version. (I tried 13.10 - too many glitches to stand a chance).
The generic nVidia driver had to be activated for OpenGl to work properly, and to avoid the black screen of death whenever the PC is brought out of 'Suspend'. I did not encounter 'MESA' - I don't think I will have to do anything Linux-specific in the Wine environment.
3D ttf fonts come out flat, and the letter 'e' is missing from the Arial font. I hope the other fonts are not so affected
To get Wave Audio and MIDI working, 'Timidity' had to be installed.
The Skype microphone was initially inactive, until going into the Skype options menu/audio. No further action was required.
Subjectively speaking, Wine seems to run programs at at about 1/3 speed, which is tolerable for now.